Systematic Reviews

The Spine Intervention Society (SIS) is committed to the comprehensive and rigorous assessment of evidence relative to diagnostic and therapeutic spinal interventions. To this end, SIS has adopted the GRADE approach to critically appraising the literature in our systematic reviews.

Current Projects

  • Fluoroscopically-Guided Lumbar Interlaminar Epidural Steroid Injections (Anticipated completion: Spring 2016)

Past Projects

  • Vorobeychik Y, Sharma A, Smith C, Miller D, Stojanovic M, Lobel S, Valley M, Duszynski B, Kennedy DJ. The Effectiveness and Risks of Non-Image-Guided Lumbar Interlaminar Epidural Steroid Injections: A Systematic Review with Comprehensive Analysis of the Published Data. Pain Medicine. 2016; DOI: pnw091 First published online: 10 June 2016 
  • Engel A, Rappard G, King W, Kennedy DJ. The Effectiveness and Risks of Fluoroscopically-Guided Cervical Medial Branch Thermal Radiofrequency Neurotomy: A Systematic Review with Comprehensive Analysis of the Published Data. Pain Medicine. 2016; 17(4): 658-669. doi 658-669 First published online: 2 February 2016 
  • Kennedy DJ, Engel A, Kreiner DS, Nampiaparampil D, Duszynski B, MacVicar J. Fluoroscopically-Guided Diagnostic and Therapeutic Intra-Articular Sacroiliac Joint Injections: A Systematic Review. Pain Medicine. 2015; 16(8): 1500-18. doi: 10.1111/pme.12833. Epub 2015 Jul 14.
  • King W, Ahmed SU, Baisden J, Patel N, Kennedy DJ, MacVicar J, Duszynski B. Diagnosis and Treatment of Posterior Sacroiliac Complex Pain: A Systematic Review with Comprehensive Analysis of the Published Data. Pain Medicine. 2015;16(2):257-65. doi: 10.1111/pme.12630.
  • Engel A, King W, MacVicar J, Standards Division of the International Spine Intervention Society. The effectiveness and risks of fluoroscopically-guided cervical transforaminal injections of steroids: A systematic review with comprehensive analysis of the published data. Pain Medicine. 2014; 15(3):386-402. doi: 10.1111/pme.12304. Epub 2013 Dec 5.
  • Kreiner D, MacVicar J, Duszynski B, Nampiaparampil D. The mild® procedure: a systematic review of the current literature. Pain Medicine. 2014; 15(2):196-205. doi: 10.1111/pme.12305. Epub 2013 Dec 5.
  • Bogduk N, Aprill C, Derby R. Lumbar discogenic pain: State-of-the-art review. Pain Medicine. 2013;14(6):813-36. doi: 10.1111/pme.12082. Epub 2013 Apr 8.
  • MacVicar J, King W, Landers MH, Bogduk N. The effectiveness of lumbar transforaminal injection of steroids: a comprehensive review with systematic analysis of the published data. Pain Medicine. 2013; 14(1):14-28. doi: 10.1111/j.1526-4637.2012.01508.x. Epub 2012 Oct 30.

To access copies of these reviews, Spine Intervention Society members have online access to all content in the journal Pain Medicine. Please follow the steps outlined on the Pain Medicine Journal page on the SIS website.

Evidence Analysis Committee


Develop systematic reviews under the direction of the Standards Division.


  1. Comply with the strategic plan as adopted by the SIS Board of Directors and ensure that the organization-wide goals of integrity and promotion of best evidence are considered in all activities.
  2. In collaboration with the Appropriate Use Criteria Committee, develop systematic reviews to serve as the basis for AUC development.
  3. In conjunction with the Standards Division, selectively review and provide commentary on relevant external practice guidelines.
  4. Perform expedited systematic reviews to assist the Health Policy Division with addressing coverage issues.
  5. Publish systematic reviews.


    Arsenio Avila, MD Jessica Jameson, MD
    Ameet S. Nagpal, MD
    Ramesh Bathina, MD Stephen Johnson, MD
    Nileshkumar Patel, MD
    Brian Boies, MD Cumhur Kilincer, MD, PhD
    Purvi Patel, MD
    Chante Buntin, MD
    Steve Lobel, MD
    Adrian Popescu, MD
    Akhil Chhatre, MD
    Vivek Loomba, MD
    George Rappard, MD
    Charles Daknis, MD
    Marc Maes, MD
    Byron Schneider, MD
    Fred DeFrancesch, MD
    Kevin Martinez, MD
    Aarti A. Singla, MD
    Lisa Doan, MD
    Ryan Mattie, MD
    Marc Valley, MD
    Jatinder Gill, MD
    Zachary McCormick, MD
    Stephen Ward, MBBS
    Alan Gonzalez-Cota, MD
    Ariz R. Mehta, MD
    Ronald Wasserman, MD
    Pragya Gupta, MD
    Maxim Moradian, MD
    Zirong Zhao, MD, PhD, FACP
    Johan Hambraeus, MD
    Jonathan Moldover, MD

Staff Contacts

Belinda Duszynski
Senior Director of Policy and Practice

Sandra Ray, MPH
Manager of Policy and Practice

Contact Us

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Hinsdale, Illinois 60521
P: 630.203.2252
Toll Free: 888.255.0005

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